Research Units

PROCESSES – Systems engineering and industrial process evaluation

The PROCESSES unit brings together a multidisciplinary team of physicists, mathematicians, electronic engineers, chemical engineers, and environmental science experts. It focuses on the design, optimization, and evaluation of biological and technological processes and systems. With an emphasis on automation and control of complex systems in the process industry, and through advanced modeling and simulation tools, it enhances industrial system performance, improves operational efficiency, and promotes sustainability. In bioprocesses, the unit applies modeling techniques to design new or improved metabolic capabilities of microorganisms, aiming at environmental protection and sustainability. It also evaluates techno-economic feasibility, eco-efficiency, risk management, and the resilience of industrial processes, particularly in the urban water cycle.

Scientific-technical capabilities

1

Design, optimization, and control of biological and technological systems.

2

Modeling and simulation techniques for industrial processes.

3

Automation of complex systems in the process industry.

4

Genomic-scale metabolic modeling for innovation and sustainability in bioprocesses.

5

Industrial computing and bioinformatics.

6

Techno-economic evaluation techniques for industrial processes.

7

Eco-efficiency analysis and risk management in industrial processes.

Researchers

RECOGNIZED RESEARCHERS

ESTABLISHED RESEARCHERS

PREDOCTORAL RESEARCHERS

RESEARCH ASSISTANTS

Current projects

Programmable metabolism bacteria for the valorization of plastic waste (ProgStrain)

This project aims to develop a bacterial strain (Paracoccus denitrificans) capable of utilizing waste from a wide variety of polyesters to produce high-value chemical compounds. Using a CRISPR-based system, the strain will be engineered to redirect its metabolic fluxes toward the desired product through the introduction of a specifically designed plasmid for the target compound.

Reference
Principal Investigator
Sergio Bordel Velasco
Date
2022-2026
Financing Entity
Fundación Ramón Areces - Ayudas a la Investigación en Ciencias de la Vida y de la Materia
Budget
€ 120,370.00

Smart water management contributing to sustainable tourism (WATOURISM)

Reference
CPP2023-010835
Principal Investigator
María Molinos Senante
Date
2024-2027
Financing Entity
MICINN / UE - Proyecto en Colaboración Público-Privada 2023
Budget
€ 95,875.00

Latest publications

Bucci, P., Cantero, D., Casas, A., Marcos, E., Menalla, E., Muñoz, R. (2026) Hydrothermal pretreatment of brewer\'s spent grain: A pathway to sustainable biogas production and waste valorization. Biomass and Bioenergy. https://doi.org/10.1016/j.biombioe.2025.108399

Montaluisa-Mantilla, M.S., Lebrero, R., García-Encina, P.A., Muñoz, R. (2026) Elucidation of the mechanisms of VOC removal in botanical filters during indoor air treatment in a test chamber. Building and Environment. https://doi.org/10.1016/j.buildenv.2025.113775

Moldes, D., Requejo, P.F., Vega, M., Bolado, S. (2026) Deep eutectic solvent-based protein recovery from microalgal biomass grown in piggery wastewater. Bioresource Technology. https://doi.org/10.1016/j.biortech.2025.133446

Vargas-Estrada, L., Bordel, S., Lebrero, R., Muñoz, R. (2026) Evaluating the experimental CO2 stripping performance of a new generation multicapillary Taylor flow reactor. Chemical Engineering and Processing-Process Intensification. https://doi.org/10.1016/j.cep.2025.110601

Martínez-Hernando, M.-P., García Álvaro, A., Ruiz Palomar, C., Suárez Rodríguez, M. del C., Bolonio, D., de Godos Crespo, I., García-Martínez, M.-J., Ortega, M.F. (2026) Sustainability assessment of a novel vehicular biomethane production from swine manure compared to conventional techniques. Waste Management. https://doi.org/10.1016/j.wasman.2025.115218

Latest Publications

Maziotis, A., Molinos-Senante, M. (2025) Benchmarking energy efficiency in wastewater treatment plants: A latent class analysis. Environmental and Sustainability Indicators. https://doi.org/10.1016/j.indic.2025.101043


Cepeda, F., Maldonado, L., Molinos-Senante, M. (2025) Householdś willingness to accept compensation for water supply interruptions caused by Wildfires: Evidence from Valparaíso, Chile. Climate Risk Management. https://doi.org/10.1016/j.crm.2025.100765


Contreras, M., Chamorro, A., Gómez, T., Echaveguren, T., Molinos-Senante, M. (2025) Bridging technical and social dimensions in critical infrastructure accessibility assessment: A case study from Chile. International Journal of Critical Infrastructure Protection. https://doi.org/10.1016/j.ijcip.2025.100811


Molinos-Senante, M., Maziotis, A. (2025) A dynamic framework for benchmarking sustainability in water utilities. Cleaner Environmental Systems. https://doi.org/10.1016/j.cesys.2025.100368


Maziotis, A., Sala-Garrido, R., Mocholi-Arce, M., Molinos-Senante, M. (2025) The economic impact of reducing greenhouse gas emissions in wastewater treatment plants: An inverse optimization approach. Environmental and Sustainability Indicators. https://doi.org/10.1016/j.indic.2025.101003


Maziotis, A., Molinos-Senante, M. (2025) Benchmarking technical efficiency of water utilities in Chile under heterogeneity: A latent class frontier approach. Utilities Policy. https://doi.org/10.1016/j.jup.2025.102076


Bausa-Ortiz, I., Oliveira-Silva, E., Muñoz, R., Cristea, S.P., de Prada, C. (2025) Moving horizon estimation in microalgae-bacteria based wastewater treatment using online and analytical multi-rate measurements. Algal Research. https://doi.org/10.1016/j.algal.2025.104338


Maziotis, A., Molinos-Senante, M. (2025) Assessing the resilience of water and wastewater utilities: A multi-criteria approach for Chile. Socio-Economic Planning Sciences. https://doi.org/10.1016/j.seps.2025.102340


Sayahi, Y., Allouche, M., Ghamgui, M., Moreau, S., Tadeo, F., Mehdi, D. (2025) Fault-Tolerant Tracking Observer-Based Controller Design for DFIG-Based Wind Turbine Affected by Stator Inter-Turn Short Circuit. Symmetry. https://doi.org/10.3390/SYM17081343


Sala-Garrido, R., Maziotis, A., Molinos-Senante, M. (2025) Assessing carbon and pollutant efficiency in wastewater treatment plants: A data-driven benchmarking framework using latent class stochastic frontier analysis. Journal of Cleaner Production. https://doi.org/10.1016/j.jclepro.2025.146413